Tumor necrosis factor alpha gene polymorphism in Serbian patients with sarcoidosis
نویسندگان
چکیده
منابع مشابه
Tumor necrosis factor alpha gene polymorphism in serbian patients with sarcoidosis.
INTRODUCTION Sarcoidosis is a multisystemic disease of unknown etiology. Genetic factors play a considerable role in the onset of the disease. Tumor necrosis factor alpha (TNF-a) is a proinflammatory cytokine which plays an important role in the pathogenesis of the disease and the formation of granuloma by regulating cellular proliferation and apoptosis. OBJECTIVE The aim of this study was to...
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Background The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), is a pathogenic element for a number of disorders. Previous studies have reported that the -1031 T/C and -238 G/A polymorphisms in the promoter region of the TNF-α gene are important factors in reproductive-related disorders. One of the most common gynecological diseases of women during the reproductive years is endo...
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S arcoidosis is an antigen-driven, multisystem, granulomatous disorder, the cause of which is not known. In a genetically susceptible individual, antigen-presenting cells trap, process, and present the putative antigen, in the context of class II major histocompatibility complex (MHC) molecules, to CD41 lymphocytes. The result of this union is a coordinated release of cytokines and chemokines, ...
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Background: Correlations between bone marrow, heart, kidney, liver, skin and lung transplant rejection or survival with human cytokine gene polymorphisms have been described. There are also reports about the role of cytokines and Tumor Necrosis Factors-Alpha (TNF-α) on corneal transplant in animal models. Further studies are needed to clarify the role of cytokines in corneal allograft rejection...
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background: the pro-inflammatory cytokine, tumor necrosis factor-alpha (tnf-α), is a pathogenic element for a number of disorders. previous studies have reported that the -1031 t/c and -238 g/a polymorphisms in the promoter region of the tnf-α gene are important factors in reproductive-related disorders. one of the most common gynecological diseases of women during the reproductive years is end...
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ژورنال
عنوان ژورنال: Srpski arhiv za celokupno lekarstvo
سال: 2013
ISSN: 0370-8179,2406-0895
DOI: 10.2298/sarh1304169r